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Clinical trials that are designed to help inform practice in the real world are referred to as pragmatic trials. They are often focused on the practical aspects of study design, including recruitment and consent in adherence, as well as the use of commonly available equipment.

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While Pragmatic Play is known for its slot machines, it also offers table games such as Bitcoin baccarat and Roulette. They have over 12 licensed titles, and their software is known for its security and reliability. Their software is available in a variety of languages and offer a variety of betting options including live dealer tables.

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Pragmatic is a software developer that provides a variety of casino games for online gambling platforms. Its iGaming software is used by leading operators as well as land-based casinos. The company provides front-end design tools, analysis tools, promotions, marketing payment systems, security, customer service and bug reporting. The company also offers security, high-quality graphics, gaming and security.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed various investigators and participants from different geographical regions. This kind of heterogeneity is necessary for pragmatic trials to be able to prove their validity and also helps reduce bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

Pragmatic Play is one of the biggest players on the live casino market, provides an array of traditional table games, including Blackjack and Roulette. Pragmatic Play's live studios in Romania and Malta offer an authentic gaming experience for its customers, as well as an extensive selection of virtual betting options. The company also offers a variety of game shows that make online gambling more exciting and interactive. Some of these shows are broadcast live and others are hosted by famous personalities from the field.

Mobile compatibility

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Pragmatic Play's slot games are very popular for both newbies as well as seasoned players. They feature modern graphics as well as traditional themes. They offer a range of paylines and bonus rounds and many offer progressive jackpots. They are not volatile so you can enjoy a long gaming experience.

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Legality

Pragmatic Play is renowned for its top-notch games, and for offering an exceptional user experience. Its software can be used on mobile devices as well as in various languages. It has been recognized as one of the leading casino gaming platforms despite its relatively young age. Wolves is one of its latest releases, a 5-reel slot machine with a hefty RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat.

The goal of pragmatic trials is to simulate real-life scenarios and gain the highest level of validity externally. They are usually requested by policy makers and practitioners to guide their decision-making. They are also a good way to identify the cause-effect relationship between an intervention and its results. However, they should not be used to substitute for explanation trials.

The concept of pragmatism is controversial and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform policy and practice decision-making. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a pragmatic study which includes the recruitment, design, and delivery of the intervention and follow-up.

The number of pragmatic trials is growing. A recent Medline query using the keywords pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary care settings.